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Critical evaluation of the MitraClip system in the management of mitral regurgitation

Authors Deuschl F, Schofer N, Lubos E, Blankenberg S, Schäfer U

Received 3 June 2015

Accepted for publication 17 September 2015

Published 11 January 2016 Volume 2016:12 Pages 1—8

DOI https://doi.org/10.2147/VHRM.S65185

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Jaya Mallela

Peer reviewer comments 3

Editor who approved publication: Professor Daniel Duprez


Florian Deuschl* Niklas Schofer* Edith Lubos, Stefan Blankenberg, Ulrich Schäfer

 Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany

*These authors contributed equally to this work

Abstract: The MitraClip (MC) system is a device for percutaneous, transseptal edge-to-edge reconstruction of the mitral valve (MV) in patients with severe mitral regurgitation (MR) not eligible for surgery. Recently, a number of studies have underlined the therapeutic benefit of the MC system for patients with extreme and high risk for MV surgery suffering from either degenerative or functional MR. The MC procedure shows negligible intraprocedural mortality, low periprocedural complication rates, and a significant reduction in MR, as well as an improvement in functional capacity and most importantly quality of life. Presently, the MC system has become an additional interventional tool in the concert of surgical methods. It hereby enlarges the spectrum of MV repair for the Heart Team. Lately, many reviews focused on the MC system. The current review describes the developments in the treatment of MR with the MC system.

Keywords: MitraClip, mitral regurgitation, percutaneous mitral valve repair

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