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Critical appraisal of bepotastine in the treatment of ocular itching associated with allergic conjunctivitis

Authors Wingard JB, Mah F

Published 15 February 2011 Volume 2011:5 Pages 201—207

DOI https://doi.org/10.2147/OPTH.S8665

Review by Single-blind

Peer reviewer comments 2


Jeremy B Wingard, Francis S Mah
UPMC Eye Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

Abstract: Bepotastine besilate 1.5% solution is an H1-antihistamine recently approved by the Food and Drug Administration for the topical treatment of ocular itching associated with allergic conjunctivitis. Several clinical studies have demonstrated its safety as well as its efficacy versus placebo. This review finds that bepotastine besilate 1.5% solution is a suitable alternative to other agents within the class of H1-antihistamines, but there are no clinical trial data to suggest that it holds any specific advantages over other agents.

Keywords: allergic conjunctivitis, antihistamine, ocular itching

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