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COVID-19 in Liver Transplant Patients: Report of 2 Cases and Review of the Literature

Authors Niknam R, Malek-Hosseini SA, Hashemieh SS, Dehghani M

Received 9 June 2020

Accepted for publication 16 July 2020

Published 31 July 2020 Volume 2020:13 Pages 317—321


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Professor Ronald Prineas

Ramin Niknam,1 Seyed Ali Malek-Hosseini,2 Seyed Saeid Hashemieh,1 Masoud Dehghani2

1Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; 2Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran

Correspondence: Masoud Dehghani
Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
Tel +989131415796

Abstract: Coronavirus 2019 (COVID-19) is caused by a novel coronavirus. Although liver injury is common in patients with COVID-19, little is known about its clinical presentation and management in liver transplantation. This is the first report from Iran that presented two cases of liver transplantation with COVID-19, neither of which had pulmonary signs and symptoms, but after diagnostic imaging, both had lung involvement. We also reviewed some literature on the management of COVID-19 in liver transplant patients. In conclusion, our patients improved after starting hydroxychloroquine and continuing to take all immunosuppressive agents except mycophenolate based on the multidisciplinary team’s decision.

Keywords: COVID-19, coronavirus, liver transplantation, immunosuppressant, management

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