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Corynebacterium urealyticum: a comprehensive review of an understated organism

Authors Salem N, Salem L, Saber S, Ismail GA, Bluth MH

Received 23 September 2014

Accepted for publication 6 January 2015

Published 21 May 2015 Volume 2015:8 Pages 129—145

DOI https://doi.org/10.2147/IDR.S74795

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Professor Suresh Antony

Nagla Salem,1 Lamyaa Salem,2 Sally Saber,2 Ghada Ismail,2 Martin H Bluth1

1Department of Pathology, Wayne State University School of Medicine, Detroit, MI, USA; 2Department of Clinical and Chemical Pathology, Ain Shams University, Cairo, Egypt

Abstract: Corynebacterium urealyticum is a Gram positive, slow-growing, lipophilic, multi-drug resistant, urease positive micro-organism with diphtheroid morphology. It has been reported as an opportunistic nosocomial pathogen and as the cause of a variety of diseases including but not limited to cystitis, pyelonephritis, and bacteremia among others. This review serves to describe C. urealyticum with respect to its history, identification, laboratory investigation, relationship to disease and treatment in order to allow increased familiarity with this organism in clinical disease.

Keywords: Corynebacterium urealyticum, cystitis, pyelonephritis, bacteremia, micro-organisms

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