RETRACTED ARTICLE: Coronin 3 Promotes the Development of Oncogenic Properties in Glioma Through the Wnt/β-Catenin Signaling Pathway

This paper has been retracted.

Wang M, Li Q, Yu S, et al. Onco Targets Ther. 2020;13:6661-6673.

We, the Editors and Publisher of OncoTargets and Therapy, have retracted the following article.

Following publication of the article, concerns were raised about the duplication of images from Figures 2, 3, 4, 6 and 7 with images from other unrelated articles. Specifically,

• Images for Figure 2B have been duplicated with images for Figure 2B from Feng Y, Xu Y, Gao Y, et al. A novel lncRNA SOX2OT promotes the malignancy of human colorectal cancer by interacting with miR-194-5p/SOX5 axis. Cell Death Dis. 2021;12:499. https://doi.org/10.1038/s41419-021-03756-y; Figure 2D from Shi Z, Zhou L, Zhou Y, et al. Inhibition of ClC-5 suppresses proliferation and induces apoptosis in cholangiocarcinoma cells through the Wnt/β-catenin signaling pathway. BMB Reports. 2022;55(6):299-304; Figures 3c and 3d from Chen Q, Tan L, Jin Z, Liu Y, Zhang Z. Downregulation of CRABP2 Inhibit the Tumorigenesis of Hepatocellular Carcinoma In Vivo and In Vitro. BioMed Research International. 2020;2020:3098327. https://doi.org/10.1155/2020/3098327 and Figure 3e from Yang R, Xing L, Zheng X, et al. RETRACTED ARTICLE: The circRNA circAGFG1 acts as a sponge of miR-195-5p to promote triple-negative breast cancer progression through regulating CCNE1 expression. Mol Cancer. 2019;18:4. https://doi.org/10.1186/s12943-018-0933-7.
• Images for Figure 2D have been duplicated with images for Figure 1C from Li C, Zhang S, Qiu T, Wang Y, Ricketts DM, Qi C. Upregulation of long non-coding RNA NNT-AS1 promotes osteosarcoma progression by inhibiting the tumor suppressive miR-320a. Cancer Biology & Therapy. 2019;20(4):413-422. https://doi.org/10.1080/15384047.2018.1538612; Figure 2C from Chen H, Pan H, Qian Y, et al. MiR-25-3p promotes the proliferation of triple negative breast cancer by targeting BTG2. Mol Cancer. 2018;17:4. https://doi.org/10.1186/s12943-017-0754-0 and Figure 4C from Chen Z, Xue C. G-Protein-Coupled Receptor 5 (LGR5) Overexpression Activates b-Catenin Signaling in Breast Cancer Cells via Protein Kinase A. Med Sci Monit Basic Res. 2019;25:15-25. https://doi.org/10.12659/MSMBR.912411.
• Images for Figure 3A have been duplicated with images for Figures 8c and 8d from Liu H, Bi J, Dong W, et al. Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis. Mol Cancer. 2018;17:161. https://doi.org/10.1186/s12943-018-0908-8.
• Images for Figure 3B have been duplicated with images for Figures 5j and 5k from Wang Y, Zeng X, Wang N, et al. Long noncoding RNA DANCR, working as a competitive endogenous RNA, promotes ROCK1-mediated proliferation and metastasis via decoying of miR-335-5p and miR-1972 in osteosarcoma. Mol Cancer. 2018;17:89. https://doi.org/10.1186/s12943-018-0837-6.
• Images for Figure 4G have been duplicated with images for Figure 5D from Chen Y, Deng Y, Chen L, Huang Z, Yan Y, Huang Z. miR-16-5p Regulates Ferroptosis by Targeting SLC7A11 in Adriamycin-Induced Ferroptosis in Cardiomyocytes. J Inflamm Res. 2023;16:1077-1089. https://doi.org/10.2147/JIR.S393646.
• Images for Figures 6B and 6D have been duplicated with images for Figures 2e and 2f from Wang Y et al (2018).
• Images for Figure 7B have been duplicated with images for Figure 3B from Feng Y, Xu Y, Gao Y, et al. A novel lncRNA SOX2OT promotes the malignancy of human colorectal cancer by interacting with miR-194-5p/SOX5 axis. Cell Death Dis. 2021;12:499. https://doi.org/10.1038/s41419-021-03756-y and Figure 7C from Liu Y, Liu R, Yang F, et al. miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1. Mol Cancer. 2017;16:53. https://doi.org/10.1186/s12943-017-0625-8.
• Images for Figure 7C have been duplicated with images for Figure 1D from Ke B, Wu X, Yang Q, et al. Yi-qi-yang-yin-tian-sui-fang enhances cisplatin-induced tumor eradication and inhibits interleukin-7 reduction in non-small cell lung cancer. Biosci Rep. 2019;39(6):BSR20190052. https://doi.org/10.1042/BSR20190052; Figure 4F from Hao J, Madigan MC, Khatri A, et al. In Vitro and In Vivo Prostate Cancer Metastasis and Chemoresistance Can Be Modulated by Expression of either CD44 or CD147. PLoS ONE. 2012;7(8):e40716. https://doi.org/10.1371/journal.pone.0040716 and Figure 5c from Chen Q, Jiang P, Jia B, et al. RCC2 contributes to tumor invasion and chemoresistance to cisplatin in hepatocellular carcinoma. Human Cell. 2020;33:709–720. https://doi.org/10.1007/s13577-020-00353-7.

The authors responded to our queries and explained that a third party was responsible for the experimental work carried out in this study. However, the authors were unable to provide details of the third party or the original data for the study. In addition, the authors did not disclose the involvement of the third party at submission or in the article. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article and the authors agree with this decision.

We have been informed in our decision-making by our editorial policies and COPE guidelines.

The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.