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Corneal lamellar grafting to repair late complications of mitomycin C trabeculectomy

Authors Fukuchi T, Matsuda H, Ueda J, Yamada A, Suda K, Abe H

Published 30 March 2010 Volume 2010:4 Pages 197—202

DOI https://doi.org/10.2147/OPTH.S8973

Review by Single-blind

Peer reviewer comments 3


Takeo Fukuchi, Hidenobu Matsuda, Jun Ueda, Akiko Yamada, Kieko Suda, Haruki Abe

Division of Ophthalmology and Visual Science, Graduated School of Medical and Dental Sciences, Niigata University, Niigata, Japan

Purpose: To report corneal lamellar grafting to repair the late-onset complications after MMC trabeculectomy.

Methods: Multiple case reports.

Results: A 76-year-old male with primary open-angle glaucoma (POAG) and a 55-year-old male with late developmental glaucoma complicated by bleb leaks from a microhole 10 and eight years after surgery, respectively. Severe ciliochoroidal detachment and a shallow anterior chamber were persistent in one case and bleb-related infection recurred in another. Additionally, a 46-year-old male with POAG had hypotony maculopathy with a giant ischemic bleb 18 months after surgery. Although these patients were quite resistant to medical and surgical treatments, they were successfully treated by corneal lamellar grafting without complications. Conclusions: Tectonic corneal lamellar grafting is a reliable and final surgical method to improve severe cases of hypotony maculopathy or bleb leak after mitomycin C trabeculectomy.

Keywords: mitomycin C, trabeculectomy, postoperative complications, hypotony maculopathy, bleb leak, corneal lamellar grafting

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