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Congenital chloride diarrhea: late presentation

Authors Al Bishi L , Mustafa

Published 4 April 2011 Volume 2011:2 Pages 35—38


Review by Single anonymous peer review

Peer reviewer comments 3

Laila Al Bishi1, Mustafa Al Toonisi2
Pediatric Department, North West Armed Forces Hospital, Tabuk, Kingdom of Saudi Arabia

Abstract: We report the case of a male infant who presented with diarrhea at 6 months of age. He was failing to thrive, and biochemical investigation revealed hypokalemic hypochloremic metabolic alkalosis. Diagnosis of congenital chloride diarrhea was suspected and confirmed by the stool chloride result. He was started on high-dose sodium chloride and potassium chloride to control the electrolyte imbalance. The disease was difficult to control for a year after diagnosis. Late presentation is associated with severe chronic electrolyte disturbances and high-dose replacement therapy.

Keywords: congenital chloride diarrhea, hypokalemic hypochloremic metabolic alkalosis, high stool chloride

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