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Clinical outcomes of wavefront-guided laser in situ keratomileusis to treat moderate-to-high astigmatism

Authors Schallhorn S, Venter J, Hannan S, Hettinger K

Received 4 May 2015

Accepted for publication 17 June 2015

Published 13 July 2015 Volume 2015:9 Pages 1291—1298

DOI https://doi.org/10.2147/OPTH.S87887

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Jie Zhang

Peer reviewer comments 5

Editor who approved publication: Dr Scott Fraser


Steven C Schallhorn,1,2 Jan A Venter,2 Stephen J Hannan,2 Keith A Hettinger2

1University of California, San Francisco, CA, USA; 2Optical Express, Glasgow, UK

Purpose: The purpose of this study was to evaluate the refractive and visual outcomes of wavefront-guided laser in situ keratomileusis (LASIK) in eyes with myopic astigmatism and cylindrical component ≥2.0 diopter (D).
Methods: In this retrospective study, 611 eyes that underwent LASIK for simple or compound myopic astigmatism were analyzed. Preoperative refractive cylinder ranged from -2.00 D to -6.00 D (mean -2.76±0.81 D), and the sphere was between 0.00 D and -9.75 D (mean -2.79±2.32 D). Predictability, visual outcomes, and vector analysis of changes in refractive astigmatism were evaluated.
Results: At 3 months after LASIK, 83.8% of eyes had uncorrected distance visual acuity of 20/20 or better, 90.3% had manifest spherical equivalent within ±0.50 D, and 79.1% had residual refractive cylinder within ±0.50 D of intended correction. The mean correction ratio for refractive cylinder was 0.92±0.14, the mean error of angle was -0.45°±2.99°, and the mean error vector was 0.37±0.38 D. A statistically significant correlation was found between the error of magnitude (arithmetic difference in the magnitudes between surgically induced refractive correction and intended refractive correction) and the intended refractive correction (r=0.26, P<0.01).
Conclusion: Wavefront-guided LASIK for the correction of myopic astigmatism is safe, effective, and predictable.

Keywords: myopic astigmatism, wavefront-guided LASIK, Hartmann–Shack aberrometer

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