Back to Journals » Clinical Ophthalmology » Volume 4

Clinical imaging and high-resolution ultrasonography in melanocytoma management

Authors Gologorsky D, Schefler AC, Ehlies FJ, Raskauskas PA, Pina Y, Williams Jr BK, Murray T 

Published 28 July 2010 Volume 2010:4 Pages 855—859


Review by Single anonymous peer review

Peer reviewer comments 5

Daniel Gologorsky1, Amy C Schefler2, Fiona J Ehlies2, Paul A Raskauskas3, Yolanda Pina2, Basil K Williams Jr4, Timothy G Murray2

1Dartmouth Medical School, Hanover, New Hampshire; 2Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida; 3Retina Consultants of Southwest Florida, Fort Myers, Florida; 4Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, USA

Purpose: To demonstrate the utility of high resolution 20 MHz ophthalmic ultrasound in serial follow-up of optic nerve head melanocytoma patients.

Methods: This study is a retrospective review of 30 patients with melanocytoma of the optic nerve head studied with echography. All patients were evaluated with standard ophthalmic A-scan and B-scan ultrasonography and 10 (33%) underwent high-resolution ultrasound.

Results: Sixty-two percent (62%) of patients had dome-shaped lesions on ultrasound, ­twenty-eight percent (28%) presented with mild elevations. The maximum elevation of any lesion was 2.6 mm. The vast majority (89%) of lesions had medium or high internal ­reflectivity and 89% demonstrated avascularity. Mean follow-up for all patients was nearly 7 years. High-resolution ultrasound enabled enhanced accuracy for detection of lesion dimensions and documentation of growth and possible malignant transformation.

Conclusions: In this study, we demonstrate a new and important role for the use of ultrasound in this disease as a complementary tool in identifying and following patients with high-risk growth characteristics. These tumor characteristics can be accurately detected with 10 MHz ultrasound in conjunction with standardized A-scan and better differentiated with the 20 MHz technology. Use of these modalities can aid in distinguishing the melanocytomas that grow from choroidal melanomas and can prevent unnecessary treatments.

Keywords: imaging, high-resolution, ultrasonography, melanocytoma

Creative Commons License © 2010 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.