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Clinical features of single and repeated globe rupture after penetrating keratoplasty

Authors Murata N, Yokogawa H, Kobayashi A, Yamazaki N, Sugiyama K

Received 27 December 2012

Accepted for publication 14 January 2013

Published 5 March 2013 Volume 2013:7 Pages 461—465

DOI https://doi.org/10.2147/OPTH.S42117

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3


Noriaki Murata, Hideaki Yokogawa, Akira Kobayashi, Natsuko Yamazaki, Kazuhisa Sugiyama

Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan

Background: In this paper, we report our experience of the clinical features of single and repeated globe rupture after penetrating keratoplasty.
Methods: We undertook a retrospective analysis of single and repeated globe ruptures following keratoplasty in eight eyes from seven consecutive patients referred to Kanazawa University Hospital over a 10-year period from January 2002 to March 2012. We analyzed their ophthalmic and demographic data, including age at time of globe rupture, incidence, time interval between keratoplasty and globe rupture, cause of rupture, complicated ocular damage, and visual outcome after surgical repair.
Results: Five patients (71.4%) experienced a single globe rupture and two patients (28.6%) experienced repeated globe ruptures. Patient age at the time of globe rupture was 75.4 ± 6.8 (range 67–83) years. Four of the patients were men and three were women. During the 10-year study period, the incidence of globe rupture following penetrating keratoplasty was 2.8%. The time interval between penetrating keratoplasty and globe rupture was 101 ± 92 months (range 7 months to 23 years). The most common cause of globe rupture in older patients was a fall (n = 5, 79.8 ± 3.7 years, all older than 67 years). Final best-corrected visual acuity was .20/200 in three eyes (37.5%). In all except one eye, globe rupture involved the graft-host junction; in the remaining eye, the rupture occurred after disruption of the extracapsular cataract extraction wound by blunt trauma.
Conclusion: Preventative measures should be taken to avoid single and repeated ocular trauma following penetrating keratoplasty.

Keywords: repeated globe ruptures, penetrating keratoplasty, postoperative complications, ocular trauma

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