Clinical and serological characteristics of Ecuadorian patients with rheumatoid arthritis
Received 14 December 2016
Accepted for publication 7 April 2017
Published 13 June 2017 Volume 2017:9 Pages 117—122
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Professor Chuan-Ju Liu
Carlos Ríos,1 Génessis Maldonado,2 Carlos Paredes,2 Christian Ferro,3 Mario Moreno,4 Claudia Vera,3 Sara Vargas,5 Wendy Calapaqui,5 Carlos Vallejo6
1Rheumatology and Rehabilitation Center, Clinical Research Department, Guayaquil, Ecuador; 2Espíritu Santo University, Rheumatology Department, Samborondón, Ecuador; 3Santiago de Guayaquil Catholic University, Rheumatology Department, Guayaquil, Ecuador; 4Luis Vernaza Hospital, Rheumatology Service, Guayaquil, Ecuador; 5Ecuadorian Society of Rheumatology, Clinical Research Department, Guayaquil, Ecuador; 6Pontificia Catholic University of Ecuador, Rheumatology Department, Quito, Ecuador
Background: Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disease, wherein late diagnosis and treatment leads to deformities and disability.
Objective: The aim of the study was to assess and describe the clinical and immunological characteristics, activity status of the disease, and functional capacity in a cohort of Ecuadorian patients with RA.
Methods: This is a cross-sectional, descriptive study conducted on a population of patients with prediagnosed RA from public and private Ecuadorian rheumatology clinics. This study investigated 400 patients with a mean age of 50 years, 353 (82.25%) of which were female.
Results: The study showed that 44.3%, 83.5%, 60.3%, 41.8%, 37.5%, and 11.5% had an acute onset of the disease, symmetrical polyarthritis, morning stiffness exceeding 1 h, dry eyes, dry mouth, and rheumatoid nodules, respectively. A total of 89.7% presented with positive rheumatoid factor, and 96.5% were anti-citrullinated protein antibody positive.
Conclusion: This is the largest Ecuadorian cohort of patients with RA; clinical features are similar to those of other Latin American populations.
Keywords: rheumatoid arthritis, epidemiology, Ecuador
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