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Clear-cornea cataract surgery: pupil size and shape changes, along with anterior chamber volume and depth changes. A Scheimpflug imaging study

Authors Kanellopoulos AJ, Asimellis G

Received 24 May 2014

Accepted for publication 19 June 2014

Published 24 October 2014 Volume 2014:8 Pages 2141—2150


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Anastasios John Kanellopoulos,1,2 George Asimellis1 Eye Institute, Athens, Greece; 2New York University School of Medicine, New York, NY, USA

Purpose: To investigate, by high-precision digital analysis of data provided by Scheimpflug imaging, changes in pupil size and shape and anterior chamber (AC) parameters following cataract surgery.
Patients and methods: The study group (86 eyes, patient age 70.58±10.33 years) was subjected to cataract removal surgery with in-the-bag intraocular lens implantation (pseudophakic). A control group of 75 healthy eyes (patient age 51.14±16.27 years) was employed for comparison. Scheimpflug imaging (preoperatively and 3 months postoperatively) was employed to investigate central corneal thickness, AC depth, and AC volume. In addition, by digitally analyzing the black-and-white dotted line pupil edge marking in the Scheimpflug “large maps,” the horizontal and vertical pupil diameters were individually measured and the pupil eccentricity was calculated. The correlations between AC depth and pupil shape parameters versus patient age, as well as the postoperative AC and pupil size and shape changes, were investigated.
Results: Compared to preoperative measurements, AC depth and AC volume of the pseudophakic eyes increased by 0.99±0.46 mm (39%; P<0.001) and 43.57±24.59 mm3 (36%; P<0.001), respectively. Pupil size analysis showed that the horizontal pupil diameter was reduced by -0.27±0.22 mm (-9.7%; P=0.001) and the vertical pupil diameter was reduced by -0.32±0.24 mm (-11%; P<0.001). Pupil eccentricity was reduced by -39.56%; P<0.001.
Conclusion: Cataract extraction surgery appears to affect pupil size and shape, possibly in correlation to AC depth increase. This novel investigation based on digital analysis of Scheimpflug imaging data suggests that the cataract postoperative photopic pupil is reduced and more circular. These changes appear to be more significant with increasing patient age.

Keywords: cataract removal, anterior chamber, pupil size, pupil eccentricity, Scheimpflug imaging, pupil changes, pseudophakic eyes, postoperative myosis

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