Characteristics of tongue and pharyngeal pressure in patients with neuromuscular diseases
Authors Umemoto G, Furuya H, Tsuboi Y, Fujioka S, Arahata H, Sugahara M, Sakai M
Received 19 January 2017
Accepted for publication 24 March 2017
Published 30 May 2017 Volume 2017:7 Pages 71—78
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Amy Norman
Peer reviewer comments 3
Editor who approved publication: Prof. Dr. Thomas Müller
George Umemoto,1 Hirokazu Furuya,2 Yoshio Tsuboi,3 Shinsuke Fujioka,3 Hajime Arahata,4 Miwa Sugahara,4 Mitsuaki Sakai5
1Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, 2Department of Neurology, Faculty of Medicine, Kochi University, Kochi, 3Department of Neurology, Faculty of Medicine, Fukuoka University, 4Department of Neurology, 5Department of Rehabilitation, Neuro-Muscular Center, National Omuta Hospital, Fukuoka, Japan
Background: Tongue and pharyngeal pressure is an essential factor associated with the swallowing function; however, little is known about the difference in tongue and pharyngeal pressure between neuromuscular diseases. This study aimed to characterize tongue and pharyngeal pressure in myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD), and amyotrophic lateral sclerosis (ALS) patients.
Methods: This study recruited 17 DMD patients, 32 DM1 patients, and 26 ALS patients. They underwent separate measurements of tongue and pharyngeal pressure under videofluoroscopy, swallowing 5 mL of barium water. We measured the largest change in pharyngeal pressure in the hypopharynx and the upper esophageal sphincter (UES) over several swallows.
Results: The mean tongue pressure (TP) was greatest in the DMD group than in the other groups (p<0.01). There was a significant difference in pressure changes in the hypopharynx and UES between the DM1 group and other groups (p<0.01). Significant correlations were observed between pressure change in the UES and the patient’s age in the DMD group (R=–0.500, p=0.045) and between pressure change in the hypopharynx and TP in the DM1 group (R=0.421, p=0.016). There was a significant correlation between pressure change in the hypopharynx and disease severity in the ALS group (R=0.435, p=0.030).
Conclusion: Patients with DMD, DM1, and ALS have weakness in the muscles involved in swallowing; however, the results of this study suggested that each disorder has a distinctive profile of impairment in the swallowing function.
Keywords: videomanofluorometry, tongue pressure, pharyngeal pressure, dysphagia,
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]