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Cerebellar dysregulation and heterogeneity of mood disorders

Authors Tobe E

Received 23 March 2014

Accepted for publication 23 May 2014

Published 23 July 2014 Volume 2014:10 Pages 1381—1384

DOI https://doi.org/10.2147/NDT.S64662

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4


Edward H Tobe

Department of Psychiatry, Cooper Medical School of Rowan University, Camden, NJ, USA

Abstract: This paper discusses diverse studies to consider the hypothesis that cerebellar pathology supports the heterogeneous metabolic pathologies of mood disorders. The evidence presented includes studies selected from the following areas of scientific research: magnetic resonance imaging, histology, clinical syndromes, comparative anatomy, neuronal connections, and mitochondrial dysfunction. The gamut of different scientific study methods confirms the validity of the involvement of the cerebellum in mood disorders.

Keywords: psychiatry, neurology, depression, cerebellum, neuropathology, heterogeneity

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