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Causes of Parkinson’s disease: Literature Review

Authors Shafique H, Blagrove A, Chung A, Logendrarajah R

Published 1 December 2011 Volume 2011:1 Pages 5—7

DOI https://doi.org/10.2147/JPRLS.S37041


Hassan Shafique,1 Alex Blagrove,2 Angela Chung,2 Raynarth Logendrarajah

1Department of Neuroscience, University of Toronto, Toronto, Ontario, Canada; 2Department of Psychology, University of Toronto, Toronto, Ontario, Canada

Abstract: Parkinson’s disease is one of the most common movement disorders in the world. Parkinson’s affects approximately 1% of all adults over the age of 60. This disorder is the result of the degeneration of dopamineproducing cells in the substantia nigra in the midbrain. Dopaminergic medications are currently being used as a treatment to improve many of the symptoms that characterize Parkinson’s disease. The cause of the disease is not yet known. However, there has been an abundance of research trying to identify potential origins. This literature review will highlight some of the main positions that researchers have on the causes of Parkinson’s disease. Among these causes are environmental toxins, genetic factors, and oxidative stress.

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