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Cardiac troponin biosensors: where are we now?

Authors Upasham S, Tanak A, Prasad S

Received 1 November 2017

Accepted for publication 19 January 2018

Published 1 March 2018 Volume 2018:4 Pages 1—13

DOI https://doi.org/10.2147/AHCT.S138543

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Gozde Durmus


Sayali Upasham, Ambalika Tanak, Shalini Prasad

Department of Biomedical Engineering, The University of Texas at Dallas, Richardson, TX, USA

Abstract: Acute myocardial infarction (AMI) is one of the leading causes of death among the cardiovascular diseases. Of several biomarkers used for detection, increased levels of cardiac troponins have proved to be significant in diagnosing AMI. This has motivated researchers in the field to develop point-of-care biosensors for rapid detection of an episode of AMI. Over the years, various detection techniques have emerged for the estimation of cardiac troponins. This review focuses on summarizing various biosensing methods, including optical, electrochemical, and acoustic techniques, for the detection of cardiac troponins.

Keywords: cardiac troponin, acute myocardial infarction, optical, electrochemical, SPR, SERS

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