Cardiac troponin biosensors: where are we now?
Received 1 November 2017
Accepted for publication 19 January 2018
Published 1 March 2018 Volume 2018:4 Pages 1—13
Checked for plagiarism Yes
Review by Single-blind
Peer reviewer comments 2
Editor who approved publication: Dr Gozde Durmus
Sayali Upasham, Ambalika Tanak, Shalini Prasad
Department of Biomedical Engineering, The University of Texas at Dallas, Richardson, TX, USA
Abstract: Acute myocardial infarction (AMI) is one of the leading causes of death among the cardiovascular diseases. Of several biomarkers used for detection, increased levels of cardiac troponins have proved to be significant in diagnosing AMI. This has motivated researchers in the field to develop point-of-care biosensors for rapid detection of an episode of AMI. Over the years, various detection techniques have emerged for the estimation of cardiac troponins. This review focuses on summarizing various biosensing methods, including optical, electrochemical, and acoustic techniques, for the detection of cardiac troponins.
Keywords: cardiac troponin, acute myocardial infarction, optical, electrochemical, SPR, SERS
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