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Brachytherapy in the treatment of cervical cancer: a review

Authors Banerjee R, Kamrava M

Received 16 January 2014

Accepted for publication 21 February 2014

Published 28 May 2014 Volume 2014:6 Pages 555—564

DOI https://doi.org/10.2147/IJWH.S46247

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Robyn Banerjee,1 Mitchell Kamrava2

1Department of Radiation Oncology, Tom Baker Cancer Centre, Calgary, Alberta, Canada; 2Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA

Abstract: Dramatic advances have been made in brachytherapy for cervical cancer. Radiation treatment planning has evolved from two-dimensional to three-dimensional, incorporating magnetic resonance imaging and/or computed tomography into the treatment paradigm. This allows for better delineation and coverage of the tumor, as well as improved avoidance of surrounding organs. Consequently, advanced brachytherapy can achieve very high rates of local control with a reduction in morbidity, compared with historic approaches. This review provides an overview of state-of-the-art gynecologic brachytherapy, with a focus on recent advances and their implications for women with cervical cancer.

Keywords: cervical cancer, brachytherapy, image-guided brachytherapy

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