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Behçet’s syndrome: providing integrated care

Authors Esatoglu SN, Kutlubay Z, Ucar D, Hatemi I, Uygunoglu U, Siva A, Hatemi G

Received 22 May 2017

Accepted for publication 29 June 2017

Published 14 August 2017 Volume 2017:10 Pages 309—319

DOI https://doi.org/10.2147/JMDH.S93681

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Akshita Wason

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser

Sinem Nihal Esatoglu,1 Zekayi Kutlubay,2 Didar Ucar,3 Ibrahim Hatemi,4 Ugur Uygunoglu,5 Aksel Siva,5 Gulen Hatemi1

1Division of Rheumatology, Department of Internal Medicine, 2Department of Dermatology, 3Department of Ophthalmology, 4Division of Gastroenterology, Department of Internal Medicine 5Department of Neurology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey

Abstract: Behçet’s syndrome (BS) is a multisystem vasculitis that presents with a variety of mucocutaneous manifestations such as oral and genital ulcers, papulopustular lesions and erythema nodosum as well as ocular, vascular, gastrointestinal and nervous system involvement. Although it occurs worldwide, it is especially prevalent in the Far East and around the Mediterranean Sea. Male gender and younger age at disease onset are associated with a more severe disease course. The management of BS depends on the severity of symptoms. If untreated, morbidity and mortality are considerably high in patients with major organ involvement. Multidisciplinary patient care is essential for the management of BS, as it is for other multisystem diseases. Rheumatologists, dermatologists, ophthalmologists, neurologists, cardiovascular surgeons and gastroenterologists are members of the multidisciplinary team. In this study, we reviewed the epidemiology, etiology, diagnostic criteria sets, clinical findings and treatment of BS and highlighted the importance of the multidisciplinary team in the management of BS.

Keywords: Behçet disease, multidisciplinary care, diagnosis, treatment, vasculitis, epidemiology, management

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