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Papers published by Dr Xiao-Wu Chen:
Repurposing paclitaxel for the treatment of fibrosis: indication discovery for existing drugs
Chen XW, Duan W, Zhou SF
Drug Design, Development and Therapy 2015, 9:4869-4871
Published Date: 7 September 2015
Novel targeting of PEGylated liposomes for codelivery of TGF-β1 siRNA and four antitubercular drugs to human macrophages for the treatment of mycobacterial infection: a quantitative proteomic study
Niu NK, Yin JJ, Yang YX, Wang ZL, Zhou ZW, He ZX, Chen XW, Zhang XJ, Duan W, Yang TX, Zhou SF
Drug Design, Development and Therapy 2015, 9:4441-4470
Published Date: 7 August 2015
Inflammation, cytokines, the IL-17/IL-6/STAT3/NF-κB axis, and tumorigenesis
Chen XW, Zhou SF
Drug Design, Development and Therapy 2015, 9:2941-2946
Published Date: 8 June 2015
The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells
Li JP, Yang YX, Liu QL, Pan ST, He ZX, Zhang X, Yang T, Chen XW, Wang D, Qiu JX, Zhou SF
Drug Design, Development and Therapy 2015, 9:1627-1652
Published Date: 16 March 2015
Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway
Niu NK, Wang ZL, Pan ST, Ding HQ, Au GHT, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF
Drug Design, Development and Therapy 2015, 9:1555-1584
Published Date: 12 March 2015
Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells
Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Pan SY, Chen XW, Zhou SF
Drug Design, Development and Therapy 2015, 9:1293-1318
Published Date: 2 March 2015
The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells
Li JP, Yang YX, Liu QL, Zhou ZW, Pan ST, He ZX, Zhang X, Yang T, Pan SY, Duan W, He SM, Chen XW, Qiu JX, Zhou SF
Drug Design, Development and Therapy 2015, 9:1027-1062
Published Date: 17 February 2015