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Attitude Towards Drug Therapy in a Community Mental Health Center Evaluated by the Drug Attitude Inventory

Authors Di Lorenzo R, Perrone D, Montorsi A, Balducci J, Rovesti S, Ferri P

Received 1 March 2020

Accepted for publication 28 April 2020

Published 17 June 2020 Volume 2020:14 Pages 995—1010


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Johnny Chen

Rosaria Di Lorenzo,1 Daniela Perrone,2 Anushree Montorsi,3 Jessica Balducci,4 Sergio Rovesti,5 Paola Ferri6

1Mental Health and Drug Abuse Department of AUSL-Modena, Psychiatric Intensive Treatment Facility, Modena 41122, Italy; 2Mental Health Department, UOC Psychiatry, Fermo 63900, Italy; 3School of Nursing, University of Modena and Reggio Emilia, Modena 41124, Italy; 4School of Specialization in Psychiatry, University of Modena and Reggio Emilia, Modena 41124, Italy; 5General and Applied Hygiene, Department of Biomedical, Metabolic and Neural Sciences, Public Health Section, Modena, 41125, Italy; 6Nursing, Department of Biomedical, Metabolic and Neural Sciences, Public Health Section, Modena, 41125, Italy

Correspondence: Rosaria Di Lorenzo Email

Introduction: Negative attitude towards drug therapy can foster limited adherence to treatment, which remains one of the biggest obstacles for implementing effective treatments, especially long term.
Purposes: The purposes of the study were 1) to evaluate the attitude towards drug therapy among a representative sample of patients treated in a community psychiatric service using 30-item Drug Attitude Inventory (DAI-30); 2) to evaluate the DAI-30 dimensions, applying factorial analysis; and 3) to highlight the socio-demographic and clinical variables correlated to DAI-30 score and factors.
Methods: The DAI was administered, over a 7-month period, to all patients treated in our psychiatric outpatient services who agreed to participate in this study and provided their informed consent. Data were statistically analyzed.
Results: With a response rate of 63.3%, 164 females and 136 males completed the DAI-30 with an average score of 14.24 (± 10.46 SD), indicating moderately positive attitude towards drug therapy. The analysis of DAI-30 internal consistency confirmed its reliability (Cronbach’s alpha=0.84). Our factorial analysis highlighted three factors: Factor 1 (Cronbach’s alpha=0.81), composed of 7 items which indicate positive, trustful attitude; Factor 2 (Cronbach’s alpha=0.78), composed of 5 items indicating negative attitude of suspiciousness; and Factor 3 (Cronbach’s alpha=0.66), composed of 4 items suggesting defensive and control attitude towards drug therapy.
Discussion: Among the selected variables, “monotherapy” and “total number of hospitalizations” were negatively correlated to the final score of DAI-30, whereas being “married” was positively correlated to it, in a statistically significant way, using the multiple linear regression model. These correlations suggest that positive attitude towards drug therapy could be reinforced by the condition of being married and reduced by relapses with hospitalization, as literature highlighted, and, paradoxically, by a monotherapy, which could suggest a sort of psychological dependence on therapy and, indirectly, on psychiatric service, potentially correlated to the long-term treatments of our patients.

Keywords: attitude towards drugs, psychiatric disorders, community mental health center, therapy adherence

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