Back to Journals » Patient Preference and Adherence » Volume 9

Assessing the adherence behavior of glaucoma patients to topical eye drops

Authors Welge-Lussen U, Weise S, Yu AL

Received 25 June 2014

Accepted for publication 4 October 2014

Published 18 December 2014 Volume 2015:9 Pages 17—23

DOI https://doi.org/10.2147/PPA.S69943

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Johnny Chen

Ulrich Welge-Lussen,1 Stefanie Weise,2 Alice L Yu3

1Department of Ophthalmology, Friedrich-Alexander University, Erlangen, Germany; 2Department of Ophthalmology, University of Cologne, Cologne, Germany; 3Department of Ophthalmology, Ludwig Maximilian University, Munich, Germany

Purpose: The goal of this study was to determine the adherence of glaucoma patients to their topical glaucoma medication. Furthermore, the relationships between the adherence behavior and the patients’ demographic data, clinical characteristics, and their knowledge about glaucoma were evaluated.
Methods: This was a prospective study of 123 patients with primary open-angle glaucoma who were given two standardized questionnaires. The first questionnaire at time point T1 comprised a knowledge assessment and the self-reported adherence measures Adherence to Refills and Medication Scale 2 (ARMS2), visual analogue scale for adherence (VAS-AD), and missed doses in the past 14 days. Two months later at time point T2, a second questionnaire reevaluated the adherence measures ARMS2, VAS-AD, and missed doses in the past 14 days.
Results: There was a good correlation among all the three adherence measures at T1 and T2. The mean values of ARMS2 were in the lower range, with 3.38 at T1 and 2.8 at T2. The VAS-AD detected that 18.5% of patients always took their eye drops correctly, and 77.9% of patients reported not to have missed a single dose in the past 14 days. There was no significant correlation between the patients’ demographic data or knowledge about glaucoma and the adherence measures ARMS2 or VAS-AD. Among the clinical characteristics, only single-eye blindness showed a significant correlation with VAS-AD.
Conclusion: In this study, no general relationships were found between medication adherence and the patients’ demographic data, clinical characteristics, or knowledge about glaucoma. It may be assumed that more individualized strategies are required to optimize adherence behavior.

Keywords: adherence, eye drops, glaucoma, medication


Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Other articles by this author:

Perioperative and postoperative risk factors for corneal graft failure

Yu AL, Kaiser M, Schaumberger M, Messmer E, Kook D, Welge-Lussen U

Clinical Ophthalmology 2014, 8:1641-1647

Published Date: 28 August 2014

Factors affecting the use of antioxidant supplements in patients with late AMD

Yu AL, Paul T, Schaumberger M, Welge-Lussen U

Clinical Ophthalmology 2014, 8:1227-1232

Published Date: 26 June 2014

Evaluation of intraocular pressure elevation after multiple injections of intravitreal ranibizumab

Yu AL, Seidensticker F, Schaumberger M, Welge-Lussen U, Wolf A

Clinical Ophthalmology 2014, 8:743-747

Published Date: 11 April 2014

Readers of this article also read:

Cancer survivors’ perspectives and experience on western medicine and traditional Chinese medicine treatment and rehabilitation: a qualitative study

Wang JW, Yang ZQ, Liu C, Chen SJ, Shen Q, Zhang TR, Partike NS, Yuan ZP, Yu JM

Patient Preference and Adherence 2015, 9:9-16

Published Date: 18 December 2014

Green synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles

Prozorova GF, Pozdnyakov AS, Kuznetsova NP, Korzhova SA, Emel’yanov AI, Ermakova TG, Fadeeva TV, Sosedova LM

International Journal of Nanomedicine 2014, 9:1883-1889

Published Date: 16 April 2014

Methacrylic-based nanogels for the pH-sensitive delivery of 5-Fluorouracil in the colon

Ashwanikumar N, Kumar NA, Nair SA, Kumar GS

International Journal of Nanomedicine 2012, 7:5769-5779

Published Date: 15 November 2012

A novel preparation method for silicone oil nanoemulsions and its application for coating hair with silicone

Hu Z, Liao M, Chen Y, Cai Y, Meng L, Liu Y, Lv N, Liu Z, Yuan W

International Journal of Nanomedicine 2012, 7:5719-5724

Published Date: 12 November 2012

Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapy

Deepa G, Thulasidasan AK, Anto RJ, Pillai JJ, Kumar GS

International Journal of Nanomedicine 2012, 7:4077-4088

Published Date: 27 July 2012

Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant

Clinical Ophthalmology 2010, 4:709-711

Published Date: 14 July 2010