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Noteworthy Comment: This study estimates hospital cost the first 48 postoperative hours for the intravenous patient-controlled analgesia (IV PCA) with opioids for 3 inpatient surgeries. Descriptive analyses using the Premier database (2010~2012) of >500 US hospitals were conducted on cost [direct acquisition and indirect cost (labor, pharmacy, etc.)] of IV PCA after total knee/hip arthroplasty (TKA/THA) or open abdominal surgeries. Although there is variation between different surgeries, hospital cost of IV PCA after major surgeries are substantial. Novel technology should demonstrate cost-effectiveness in addition to clinical superiority.

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Cost of opioid intravenous patient-controlled analgesia: results from a hospital database analysis and literature assessment

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