Application and tolerability of Herpotherm^® in the treatment of genital herpes

Gerrit Schlippe,¹ Werner Voss,¹ Lars Christian Brenn<sup>2

1</sup>Dermatest Medical Research Company, Münster, Germany; ²RIEMSER Pharma GmbH, Greifswald, Germany

Abstract: Genital herpes is the manifestation of a herpes simplex virus 2 infection. Standard treatment uses both local and systemic approaches. Here, we report on the results of a local therapy approach with 31 female patients at a gynecological practice. In the here-described approach, established genital herpes infection was treated with the medical device Herpotherm^®, with or without virostatic drugs. Herpotherm^® is a certified medical device operating on the basis of local heat application. Parameters evaluated during the approach were (i) subjective patient assessments and (ii) objective assessment of the physician. In the described therapy approach a positive effect in terms of nature and severity in the course of the disease using Herpotherm^® could be demonstrated. It could be shown that Herpotherm^® can also be used for genital herpes and that it is well tolerated. In relation to other therapies using topical treatment for genital herpes, an extremely rapid reduction of pain and herpetic symptoms could be observed. Intolerances or discontinued use as a result of complications were not observed.

Keywords: herpes simplex virus, local heat, virostatic