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Apnea of prematurity: challenges and solutions

Authors Picone S, Aufieri R, Paolillo P

Received 4 March 2014

Accepted for publication 22 April 2014

Published 19 June 2014 Volume 2014:4 Pages 101—109

DOI https://doi.org/10.2147/RRN.S44810

Checked for plagiarism Yes

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Peer reviewer comments 2


Simonetta Picone, Roberto Aufieri, Piermichele Paolillo

Division of Neonatology and Neonatal Intensive Care, Department of Maternal and Child Health, Casilino General Hospital, Rome, Italy

Abstract: Apnea of prematurity is a developmental disorder that frequently affects preterm infants, especially those with lower gestational age. Even if apnea of prematurity is by definition a self-limiting condition, it can cause serious problems during the hospital stay and can potentially have long-term neurological and cognitive consequences depending on the severity and intensity of the episodes. The diagnosis of apnea of prematurity can be made only after excluding a number of diseases of the preterm infant in which apnea may be an epiphenomenon. Etiological diagnosis is essential for selection of appropriate treatment, which may be nonpharmacological or involve use of drugs.

Keywords: apnea of prematurity, idiopathic and secondary apnea, caffeine

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