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Anxiety and depression in women with and without chronic pelvic pain: prevalence and associated factors

Authors Siqueira-Campos VM, Da Luz RA, de Deus JM, Martinez EZ, Conde DM

Received 22 November 2018

Accepted for publication 14 February 2019

Published 16 April 2019 Volume 2019:12 Pages 1223—1233


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Michael A Überall

Vânia Meira e Siqueira-Campos,1 Rosa Azevedo Da Luz,2 José Miguel de Deus,2,3 Edson Zangiacomi Martinez,4 Délio Marques Conde1,3

1Postgraduate Program in Health Sciences, Federal University of Goiás, Goiânia, Goiás, Brazil; 2Teaching Hospital, Women’s Health Unit, Federal University of Goiás, Goiânia, Goiás, Brazil; 3Department of Gynecology and Obstetrics, Federal University of Goiás, Goiânia, Goiás, Brazil; 4Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil

Objectives: To investigate the prevalence of anxiety, depression and mixed anxiety and depressive disorder (MADD) and factors associated with these conditions in women with chronic pelvic pain (CPP) compared to a pain-free control group.
Methods: A cross-sectional study was conducted with 100 women with CPP and 100 without CPP. The Hospital Anxiety and Depression Scale (HADS) was used to evaluate the presence of anxiety and depression. Sociodemographic, behavioral and clinical characteristics were investigated. Fisher’s exact test was used to compare characteristics between groups. A log-binomial regression model was used, with adjustment for age, skin color, schooling, body mass index and pain. Prevalence ratios (PR), together with their 95% confidence intervals (CI), were calculated to investigate factors associated with anxiety, depression and MADD.
Results: The prevalence of anxiety was 66% in the CPP group and 49% in the controls (p=0.02). Depression was identified in 63% of the women with CPP and in 38% of the controls (p<0.01). MADD was present in 54% of the CPP group and in 28% of the controls (p<0.01). In the adjusted analysis, CPP (PR=1.3; 95%CI: 1.1–1.6), physical abuse (PR=1.5; 95%CI: 1.2–1.8) and sexual abuse (PR=1.5; 95%CI: 1.1–1.8) were independently associated with anxiety. Women of 25 to 34 years of age were less likely to have anxiety (PR=0.6; 95%CI: 0.4–0.8). CPP (PR=1.6; 95%CI: 1.2–2.2), physical abuse (PR=1.3; 95%CI: 1.1–1.7) and sexual abuse (PR=1.7; 95%CI: 1.3–2.2) were independently associated with depression. CPP (PR=1.9; 95%CI: 1.3–2.7), smoking (PR=1.5; 95%CI: 1.1–2.1), physical abuse (PR=1.4; 95%CI: 1.1–1.9) and sexual abuse (PR=1.4; 95%CI: 1.1–1.8) were independently associated with MADD.
Conclusions: The prevalence of anxiety, depression and MADD was higher in women with CPP compared to the pain-free controls. Factors associated with mental disorders were identified. The independent association between CPP and anxiety, depression and MADD was noteworthy. These findings suggest that systematic management of psychological factors could contribute towards improving the mental health of these women.

Keywords: sexual abuse, physical abuse, age, smoking, women’s health

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