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Anxiety and Depression in Eosinophilic Esophagitis: A Scoping Review and Recommendations for Future Research

Authors Taft TH, Guadagnoli L, Edlynn E

Received 5 September 2019

Accepted for publication 27 November 2019

Published 9 December 2019 Volume 2019:12 Pages 389—399

DOI https://doi.org/10.2147/JAA.S193045

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Luis Garcia-Marcos


Tiffany H Taft,1 Livia Guadagnoli,1 Emily Edlynn2

1Northwestern University Feinberg School of Medicine, Division of Gastroenterology & Hepatology, Chicago, IL, USA; 2Oak Park Behavioral Medicine LLC, Oak Park, IL, USA

Correspondence: Tiffany H Taft
Northwestern University Feinberg School of Medicine, Division of Gastroenterology & Hepatology, 676 N. Saint Clair Street, Suite 1400, Chicago, IL 60610, USA
Tel +1 312-725-6175
Email ttaft@northwestern.edu

Abstract: Eosinophilic esophagitis (EoE) is a rapidly emerging chronic disease with limited treatments. Impacting both children and adults, EoE and its treatments have the potential to significantly reduce psychological functioning, including increasing anxiety and depression. In this paper, we provide a scoping review of the scientific literature on anxiety and depression in both pediatric and adult patients. We aim to document the current state of research, identify knowledge gaps, recognize unique challenges that EoE patients may face as they relate to psychosocial function, and offer suggestions for future research directions. Based on the current review, both adult and pediatric patients with EoE are at risk for anxiety and depression symptoms, both due to the disease process and the prevailing dietary treatments. Significant gaps exist in the current understanding of anxiety and depression in EoE, providing ample opportunity for future studies to address this important issue.

Keywords: eosinophilic esophagitis, anxiety, depression, quality of life, scoping review

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