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Antitussives and substance abuse

Authors Burns J, Boyer E

Received 21 July 2013

Accepted for publication 18 September 2013

Published 6 November 2013 Volume 2013:4 Pages 75—82

DOI https://doi.org/10.2147/SAR.S36761

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2



Jarrett M Burns, Edward W Boyer

Division of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA, USA

Abstract: Abuse of antitussive preparations is a continuing problem in the United States and throughout the world. Illicit, exploratory, or recreational use of dextromethorphan and codeine/promethazine cough syrups is widely described. This review describes the pharmacology, clinical effects, and management of toxicity from commonly abused antitussive formulations.

Keywords: dextromethorphan, purple drank, sizzurp, codeine/promethazine

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