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Antiplatelet combinations for prevention of atherothrombotic events

Authors Bollati M, Gaita F, Anselmino M

Published 12 January 2011 Volume 2011:7 Pages 23—30

DOI https://doi.org/10.2147/VHRM.S12271

Review by Single-blind

Peer reviewer comments 2


Mario Bollat,i Fiorenzo Gaita, Matteo Anselmino
Department of Internal Medicine, Division of Cardiology, University of Torino, Italy

Abstract: Antiplatelet therapy plays a fundamental role in reducing atherothrombotic events by several pathways. The present work reviews available evidence on antiplatelet therapy both for primary prevention and in the presence of established peripheral, cerebral, or cardiac ischemic disease. Due to the importance of adherence to therapy to achieve optimal effects, special attention is given to the use of fixed-dose oral formulations in the clinical subset of patients in whom double antiplatelet therapy has proven indications.

Keywords: aspirin, clopidogrel, ticlopidine, fixed-dose combinations
 

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