Back to Journals » International Journal of General Medicine » Volume 7

Antibiotics for the treatment of rheumatoid arthritis

Authors Ogrendik M

Received 1 November 2013

Accepted for publication 14 November 2013

Published 27 December 2013 Volume 2014:7 Pages 43—47


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Mesut Ogrendik

Division Physical Therapy and Rheumatology, Nazilli State Hospital, Nazilli, Turkey

Abstract: Antibiotic treatment for rheumatoid arthritis (RA) commenced in the 1930s with the use of sulfasalazine. Later, tetracyclines were successfully used for the treatment of RA. In double-blind and randomized studies, levofloxacin and macrolide antibiotics (including clarithromycin and roxithromycin) were also shown to be effective in the treatment of RA. There have been several reports in the literature indicating that periodontal pathogens are a possible cause of RA. Oral bacteria are one possible cause of RA. In this review, we aimed to investigate the effects of different antibiotics in RA treatment.

Keywords: oral bacteria, treatment, disease-modifying antirheumatic drugs, periodontitis

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]