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Antibiotics for the treatment of rheumatoid arthritis

Authors Ogrendik M

Received 1 November 2013

Accepted for publication 14 November 2013

Published 27 December 2013 Volume 2014:7 Pages 43—47

DOI https://doi.org/10.2147/IJGM.S56957

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Mesut Ogrendik

Division Physical Therapy and Rheumatology, Nazilli State Hospital, Nazilli, Turkey

Abstract: Antibiotic treatment for rheumatoid arthritis (RA) commenced in the 1930s with the use of sulfasalazine. Later, tetracyclines were successfully used for the treatment of RA. In double-blind and randomized studies, levofloxacin and macrolide antibiotics (including clarithromycin and roxithromycin) were also shown to be effective in the treatment of RA. There have been several reports in the literature indicating that periodontal pathogens are a possible cause of RA. Oral bacteria are one possible cause of RA. In this review, we aimed to investigate the effects of different antibiotics in RA treatment.

Keywords: oral bacteria, treatment, disease-modifying antirheumatic drugs, periodontitis

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