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Anterior segment biometry using ultrasound biomicroscopy and the Artemis-2 very high frequency ultrasound scanner

Authors Al-Farhan H, AlMutairi R

Received 23 October 2012

Accepted for publication 13 December 2012

Published 16 January 2013 Volume 2013:7 Pages 141—147

DOI https://doi.org/10.2147/OPTH.S39463

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Haya M Al-Farhan, Reem N AlMutairi

King Saud University, College of Applied Medical Sciences, Department of Optometry and Vision Sciences, Riyadh, Kingdom of Saudi Arabia

Purpose: To compare the precision of anterior chamber angle (ACA) and anterior chamber depth (ACD) measurements taken with ultrasound biomicroscopy (UBM) and the Artemis-2 Very High Frequency Ultrasound Scanner (VHFUS) in normal subjects.
Design: Prospective study.
Methods: We randomly selected one eye from each of 59 normal subjects in this study. Two subjects dropped out of the study; the associated data were excluded from analysis. ACA and ACD measurements were obtained using the VHFUS and the UBM. The results were compared statistically using repeated-measures analysis of variance for the intraobserver repeatability, unpaired t-test, and limits of agreement.
Results: The average ACA values for the UBM and the VHFUS (±standard deviation) were 41.83° ± 5.03° and 33.36° ± 6.03°, respectively. The average ACD values were 2.96 ± 0.34 mm and 2.87 ± 0.31 mm. The intraobserver repeatability analysis of variance P-values for ACA and ACD measurements using UBM were 0.10 and 0.68, respectively; for the Artemis-2 VHFUS, the respective values were 0.68 and 0.09. The difference in ACA measurements was statistically significant (t = 8.41; P < 0.0001), while the difference in ACD values was not (t = 1.51; P < 0.13). The mean ACA difference was 8.50° ± 2.50°, and the limits of agreement were +13.30° to −3.60°. The mean ACD difference was 0.09 ± 0.27 mm, and the limits of agreement ranged from 0.61 mm to −0.43 mm. The mean difference percentage of ACD was 3.1% for both instruments.
Conclusion: In case of the ACD, both instruments can be used interchangeably; however, with the ACA instruments, they cannot be used interchangeably.

Keywords: anterior chamber angle, anterior chamber depth, Artemis-2 VHF scanner, ultrasound biomicroscope, normal eyes

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