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Analgesic effect of 30% glucose, milk and non-nutritive sucking in neonates

Authors Mekaoui N, Issef, Kabiri M, Barkat A

Received 8 February 2012

Accepted for publication 31 July 2012

Published 21 November 2012 Volume 2012:5 Pages 573—577

DOI https://doi.org/10.2147/JPR.S30665

Review by Single-blind

Peer reviewer comments 3

Nour Mekkaoui,1 Imane Issef,1 Meryem Kabiri,1,2 Amina Barkat1,3

1
Neonatology and Intensive Care Unit, National Reference Center in Neonatology and Nutrition, Children’s Hospital of Rabat, Rabat; 2CRECET, Faculty of Medicine and Pharmacy, Rabat; 3Research Team of Health and Nutrition, Faculty of Medicine and Pharmacy, Mohammed V University, Souissi, Rabat, Morocco

Background: The aim of this study was to evaluate nondrug management practices concerning pain induced by blood sampling in newborns in a Moroccan neonatal unit and to determine whether the results reported from a randomized clinical study of nondrug analgesia could be reproduced in a routine care setting.
Methods: Standardized prospective observation of analgesic practices used during blood sampling was performed. Pain was assessed using the Douleur Aiguë Nouveau-né (DAN, [Newborn Acute Pain]) scale that incorporates facial expression, vocal expression, and limb movements of the newborn during realization of a painful procedure. Five different nondrug analgesic practices were investigated in 125 infants.
Results: Median DAN scores for the five methods were 6 (1–10) for venous sampling with oral administration of 30% glucose, 5 (1–10) for venous sampling with sucking, 3 (0–6) for venous sampling with oral administration of 30% glucose combined with sucking, 4 (0–10) for venous sampling with oral administration of 30% glucose combined with sucking and administration of 2 mL of adapted infant formula, and 6 (3–8) for venous sampling with administration of 2 mL of adapted infant formula.
Conclusion: Oral administration of 30% glucose combined with sucking provided better control of pain induced by blood sampling in newborns at our neonatal unit.

Keywords: pain, neonate, assessment, 30% glucose, sucking

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