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An evidence-based review of NX1207 and its potential in the treatment of benign prostatic hyperplasia

Authors Kunit T, Lusuardi L

Received 31 January 2014

Accepted for publication 11 May 2014

Published 12 July 2014 Volume 2014:6 Pages 67—70

DOI https://doi.org/10.2147/RRU.S46047

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3


Thomas Kunit, Lukas Lusuardi

Department of Urology and Andrology, Paracelsus Medical University Salzburg, Salzburg, Austria

Abstract: In elderly men, benign prostatic hyperplasia is often associated with lower urinary tract symptoms, and its prevalence rises with age. Lower urinary tract symptoms can be very bothersome and lead to a decrease in health-related quality of life. Furthermore, benign prostatic hyperplasia is a progressive disease that can lead to serious complications like acute urinary retention. Medical treatment with α1-blockers or 5α-reductase inhibitors is recommended by the European Association of Urology. On the other hand, there are some new innovations such as NX1207. The aim of this review is to summarize the published data. NX1207 is a new drug that is administered by transrectal intraprostatic injection under ultrasound guidance. The substance leads to prostate volume reduction and symptomatic improvement. However, patient numbers are still low and currently treatment with NX1207 is still experimental.

Keywords: BPH, NX 1207, hyperplasia, LUTS, prostate

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