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Comparative Effectiveness Research

Aims and Scope

Comparative Effectiveness Research is an international, peer reviewed, open access journal that strives to cover this emerging field. Comparative effectiveness research (CER) is a PICOT (Population, Intervention, Comparison, Outcome, Time) question-driven, systematic process of investigation; it utilizes the well-characterized design of research synthesis, validated methodology for assessing the evidence and data analysis, which includes acceptable sampling and meta-analysis. CER assembles the best available evidence for ensuring effectiveness-focused, patient-centered and evidence-based medicine, dentistry, nursing and allied disciplines. CER is the critical and timely process of translational healthcare; it evinces the most reliable evidence to compare the advantages, disadvantages and expenditure for an intervention with other available options for the prevention, diagnosis, treatment and monitoring of a clinical condition. CER amalgamates patients, clinicians, caregivers and other stakeholders to improve evidence-based clinical decision-making that will enhance healthcare at the discrete and population levels.

The journal will consider publishing material in the following areas:
* Comparativeness effectiveness discoveries in therapeutics, diagnostics, surgery, medical and dental devices and other healthcare spheres
* Methodology of CER studies (e.g., validation of new instruments to quantify the level or the quality of the evidence; meta-analysis inference models; individual patient outcomes research and analysis)
* Head-to-head comparisons of current treatments - excluding CER analysis (i.e., comparisons of efficacy, cost, quality of life and related data for alternate interventions)
* Evaluations of the positives and negatives of specific healthcare options for patient groups, including tele-healthcare, stakeholder engagement, health literacy and CER domains related to the realm of translational effectiveness.
* Evaluation and interpretation of CER reports (i.e., systematic reviews), and derived critical reviews
*  Research design and decision analysis (i.e., advances in research synthesis, and models of effectiveness-focused, patient-centered and evidence-based clinical decision-making, such as the Logic-based model vs. the Markovian frequency-based model)

NOTE: Authors should show evidence of using the following guidelines when submitting material for publication: CONSORT-10 for a clinical trial, PRISMA for a systematic review with or without meta-analysis (authors should offer a solid rationale as to why any submission lacks a meta-analysis), STROBE for observational studies and GRADE and AGREE if the submission pertains to implications to evidence-based practice.

Please see:  for further details