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Administration of the fixed combination of latanoprost 0.005% and timolol 0.5% in glaucoma patients with an intraocular pressure over 30 mmHg
Authors Ozkurt Y, Sengor T, Evciman T, Haboğlu M, Baş G, Aydın S
Published 8 May 2009 Volume 2009:3 Pages 337—339
DOI https://doi.org/10.2147/OPTH.S5128
Review by Single anonymous peer review
Peer reviewer comments 3
Yelda Buyru Özkurt, Tomris Sengor, Tufan Evciman, Melih Haboglu, Gökçen Baş, Sevda Aydın
Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey
Purpose: To evaluate the intraocular pressure (IOP) reducing effect of a fixed combination of 0.005% latanoprost and 0.5% timolol in patients with an IOP of 30 mmHg or higher.
Design: Prospective, randomized clinical trial.
Participants: Twenty-eight patients.
Methods: Patients had received no prior medical glaucoma treatment. Routine ophthalmic examinations and visual field tests were performed before and after treatment for each patient.
Results: Mean IOP was 32.28 ± 0.92 mmHg before treatment. Mean IOP levels were 18.75 ± 0.68 for the first day, 17.96 ± 0.90 for the first week and 17.64 ± 0.66 for the first month after treatment.
Conclusion: A fixed combination of latanoprost 0.005% and timolol 0.5% is effective in significantly reducing IOP in glaucoma patients with an IOP greater than 30 mmHg.
Keywords: latanoprost, timolol, combination, glaucoma, intraocular pressure
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