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Adherence with Medical Therapy for Primary Open-Angle Glaucoma in Kenya – A Pilot Study

Authors Murdoch I, Nyakundi D, Baker H, Dulku S, Kiage D

Received 29 October 2019

Accepted for publication 18 December 2019

Published 10 February 2020 Volume 2020:14 Pages 221—225

DOI https://doi.org/10.2147/PPA.S236468

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Johnny Chen


Ian Murdoch, 1 David Nyakundi, 2 Helen Baker, 1 Simon Dulku, 3 Daniel Kiage 2

1Institute of Ophthalmology, London EC1V 9EL, UK; 2Innovation Eye Centre Ltd, Kisii, Kenya; 3University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2WB, UK

Correspondence: Ian Murdoch
Institute of Ophthalmology, Bath Street, London EC1V 9EL, UK
Email i.murdoch@ucl.ac.uk

Background/Objectives: Adherence is a major challenge in topical glaucoma therapy, particularly in an African context. We report a pilot study assessing adherence independently for the first time in an African context.
Subjects/Methods: Participants with newly diagnosed open-angle glaucoma received a weighed bottle of Lumigan 0.01% with counselling on therapy. The bottles were returned monthly for renewal and weighed on return to estimate drops taken during the period. Data collection was for one year with a short compliance questionnaire.
Results: 11 patients participated. 5 (45%) failed to complete one full year of topical therapy. The overall mean number of drops per eye per day was 1.74 (SD 0.69) for the 6 with one year of monthly returned bottles and controlled IOPs at each visit. Self-perception of compliance in these patients was good.
Conclusion: The signs of poor adherence based on both self-report (previous literature), and in this small-scale study of an objective measure suggest medication may not be the first-line treatment of choice in this environment. Our report does, however, raise the possibility that those patients who return for repeat prescriptions and review are indeed adhering to their treatment regimens.

Keywords: adherence, glaucoma, Africa, medical treatment

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