Back to Journals » HIV/AIDS - Research and Palliative Care » Volume 2

Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice

Authors Monjok E, Smesny A, Okokon IB, Mgbere O, Essien EJ

Published 30 March 2010 Volume 2010:2 Pages 69—76

DOI https://doi.org/10.2147/HIV.S9280

Review by Single-blind

Peer reviewer comments 2


Emmanuel Monjok1, Andrea Smesny1, Ita B Okokon2, Osaro Mgbere3, E James Essien1

1Institute of Community Health, University of Houston, Texas Medical Center, Houston Texas 77030, USA; 2Department of Family Medicine, University of Calabar Teaching Hospital, Calabar, Nigeria; 3Bureau of Epidemiology, Houston Department of Health and Human Services, Houston, Texas 77054, USA

Abstract: Both Human Immunodeficiency Virus (HIV) infection and AIDS remain major public health crises in Nigeria, a country which harbors more people living with HIV/AIDS than any country in the world, with the exception of South Africa and India. In response to the HIV pandemic, global and international health initiatives have targeted several countries, including Nigeria, for the expansion of antiretroviral therapy (ART) programs for the increasing number of affected patients. The success of these expanded ART initiatives depends on the treated individual’s continual adherence to antiretroviral (ARV) drugs. Thirteen peer-reviewed studies concerning adherence to ART in Nigeria were reviewed with very few pediatric and adolescent studies being found. Methodologies of adherence measurement were analyzed and reasons for nonadherence were identified in the geopolitical zones in the federal republic of Nigeria. The results of the literature review indicate that adherence to ART is mixed (both high and low adherence) with patient self-recall identified as the common method of assessment. The most common reasons identified for patient nonadherence include the cost of therapy (even when the drugs are heavily subsidized), medication side effects, nonavailability of ARV drugs, and the stigma of taking the drugs. This manuscript highlights the policy and practice implications from these studies and provides recommendations for future ART program management.
Keywords: adherence, antiretroviral therapy (ART), HIV, PLWHA, Nigeria

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]