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Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review

Authors Abdulla MA, Al Saeed M, Ameer Alshaikh S, Nabar UJ

Received 1 April 2017

Accepted for publication 17 August 2017

Published 6 November 2017 Volume 2017:10 Pages 367—372

DOI https://doi.org/10.2147/IMCRJ.S138616

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Amy Norman

Peer reviewer comments 4

Editor who approved publication: Professor Ronald Prineas


Maheeba Abdulla Mohamed Abdulla,1 Mahmood Al Saeed,1 Safa Ameer Alshaikh,2 Umesh J Nabar3

1Department of Internal Medicine, 2Department of Pathology, 3Department of Radiology, Salmaniya Medical Complex, Manama, The Kingdom of Bahrain

Introduction: Alimentary tract cystic duplication is a rare congenital anomaly predominantly affecting females, and diagnosed mostly in the early years of life.
Case report: We present here a case of a 51-year-old man presenting with a 2-day history of melena. Gastroscopy showed fresh blood, as well as a mass lesion and cavity at the fundus. Biopsies of the mass edge reported the occurrence of moderately differentiated adenocarcinoma and mild chronic gastritis. Computed tomography imaging showed a 5.1×6.5 cm cystic mass in the gastric greater curvature. The patient received six cycles of epirubicin, capecitabine, and oxaliplatin, followed by uncomplicated total gastrectomy.
Literature review: Data from all 11 reports of similar cases were reviewed and pooled. The result shows male predominance and variable symptoms, as well as a wide age range (25–76 years) at presentation. The cysts are commonly located along the greater curvature and are unilocular. Surgery was the treatment in most cases.
Conclusion: Alimentary tract cystic duplication is rare and may predispose to malignancy. Early diagnosis and prompt surgical intervention is important for the best outcome.

Keywords: gastric duplication cyst, gastric mass, adenocarcinoma, cystic duplication, alimentary tract cystic duplication

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