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Adaptive optics assisted visualization of thickened retinal arterial wall in a patient with controlled malignant hypertension

Authors Arichika S, Uji A, Yoshimura N

Received 30 July 2014

Accepted for publication 3 September 2014

Published 6 October 2014 Volume 2014:8 Pages 2041—2043

DOI https://doi.org/10.2147/OPTH.S71964

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Shigeta Arichika, Akihito Uji, Nagahisa Yoshimura

Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Purpose: We aimed to visualize the retinal arterial wall thickness, assisted by noninvasive adaptive optics scanning laser ophthalmoscopy (AO-SLO).
Methods: The arterial wall thickness was measured and compared between one normal subject and one patient suffering from malignant hypertensive retinopathy.
Results: Increased arterial wall thickness was revealed with a newly developed AO-SLO system, in a retinal artery of 1-papilla diameter temporal inferior to the optic disc. The average wall thickness, with hypertension, was 18.7 µm, and the wall-to-lumen ratio was 0.44, both bigger than normal.
Conclusion: AO-SLO enabled us to evaluate the retinal wall thickness in the hypertensive patient. The arterial walls were thickened compared with normal. AO-SLO may facilitate future noninvasive study of arterial walls in human medicine.

Keywords: wall thickness, AO-SLO, hypertensive retinopathy

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