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Acute macular edema following intracorporeal prostaglandin injection for erectile dysfunction

Authors Asahi M, Chou C, Gallemore R

Received 2 April 2015

Accepted for publication 15 May 2015

Published 22 July 2015 Volume 2015:8 Pages 141—144


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Editor who approved publication: Dr Scott Fraser

Masumi G Asahi, Calvin Chou, Ron P Gallemore

Retina Macula Institute, Torrance, CA, USA

Purpose: We aimed to describe the first case of macular edema following intracorporeal injection of alprostadil, a prostaglandin E1.
Methods: This was a retrospective case report followed with optical coherence tomography, fundus photos, and fluorescein angiography images.
Results: A patient developed bilateral cystoid macular edema following intracorporeal injection of alprostadil, a prostaglandin E1 for treatment of erectile dysfunction. The edema resolved following treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids, with subsequent recovery in visual acuity.
Discussion: Systemic prostaglandin administration can cause macular edema and vision loss, indicating that elevated systemic prostaglandin levels may affect visual function. This has potential implications for other systemic disorders and treatments that could affect macular function.

Keywords: alprostadil, inflammation

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