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Ability of a neuro-ophthalmologist to estimate retinal nerve fiber layer thickness

Authors Pula J, Kattah J, Wang, Marshall J, Eggenberger E

Received 2 June 2012

Accepted for publication 24 July 2012

Published 11 September 2012 Volume 2012:6 Pages 1477—1481


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

John H Pula,1 Jorge C Kattah,1 Hauping Wang,1 John Marshall,1 Eric R Eggenberger2

1University of Illinois College of Medicine at Peoria, Illinois Neurologic Institute, Peoria, IL, USA; 2Michigan State University, East Lansing, MI, USA

Background: Qualitative description of the optic disc has clinical value, but optical coherence tomography (OCT) has provided the ability to quantify retinal nerve fiber layer (RNFL) thickness.
Methods: We asked three neuro-ophthalmologists of at least 20 years’ experience to estimate the average OCT RNFL thickness of 37 eyes based on fundus photos.
Results: The overall correlation coefficient for RNFL thickness estimation variance between two physicians and between physician and OCT was 0.53. The likelihood that the RNFL thickness estimation between physicians, or between physician and OCT, was within 10 µm of each other was 47%–62%. All physicians had disparities in RNFL thickness estimation greater than 30 µm.
Conclusion: This study provides information on the ability of an experienced neuro- ophthalmologist to estimate the RNFL thickness based on fundus photos.

Keywords: optical coherence tomography, OCT, RNFL, retinal nerve fiber, estimation

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