A Review of Neuromodulation in the Treatment of Cardiovascular Disease
Received 26 October 2019
Accepted for publication 3 December 2019
Published 18 February 2020 Volume 2020:11 Pages 7—18
Checked for plagiarism Yes
Review by Single-blind
Peer reviewer comments 2
Editor who approved publication: Dr Richard Kones
Ajax Yang,1 Krishnan V Chakravarthy,2 Jason E Pope,3 Timothy R Deer4
1Department of Anesthesiology, New York-Presbyterian Hospital/Weill Cornell Medicine, New York, NY, USA; 2Department of Anesthesiology and Pain Medicine, University of California San Diego Health Sciences, La Jolla, CA; VA San Diego Healthcare System, San Diego, CA, USA; 3Evolve Restorative Center, Santa Rosa, CA, USA; 4Center for Pain Relief, Charleston, WV, USA
Correspondence: Timothy R Deer
Center for Pain Relief, 400 Court Street, Suite 100, Charleston, WV 25301, USA
Tel +1304 347 6120
Introduction: The algorithmic use of neurostimulation to treat chronic pain is routine. However, it is underutilized in managing pain and other symptoms relating to cardiovascular dysfunctions. The goal of this article is to focus on the clinical results from using spinal cord stimulation (SCS) in the realm of cardiovascular medicine.
Material and Methods: The current literature was reviewed, summarized and tabulated. This manuscript contains results from systematic reviews, randomized clinical trials and observational study search results on PubMed spanning the last 30 years. The official positioning statement from the International Neuromodulation Society Neuromodulation Appropriateness Consensus Committee (NACC) was also highlighted.
Results: Evidence supports that SCS is asafe, reversible, minimally-invasive and efficacious modality to mitigate chronic symptoms of refractory angina pectoris and critical limb ischemia.
Discussion: Spinal cord stimulation is effective in providing relief, improve quality of life and functional mobility in patients living with ischemic pain of systemic arterial occlusive disease.
Conclusion: Spinal cord stimulation should be considered early in the treatment algorithm among individuals with inoperable ischemic pain.
Keywords: angina pectoris, critical limb ischemia, ischemic pain, congestive heart failure, Reynaud’s syndrome, spinal cord stimulation
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