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A patient with acute macular neuroretinopathy and central retinal vein occlusion

Authors Hirooka K, Saito W, Noda K, Ishida S

Received 21 April 2013

Accepted for publication 14 June 2013

Published 15 July 2013 Volume 2013:7 Pages 1447—1450

DOI https://doi.org/10.2147/OPTH.S47045

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3


Kiriko Hirooka,1 Wataru Saito,1,2 Kousuke Noda,1,2 Susumu Ishida1,2

1Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Japan; 2Department of Ocular Circulation and Metabolism, Hokkaido University Graduate School of Medicine, Sapporo, Japan

Purpose: The precise mechanism causing acute macular neuroretinopathy (AMN) is still unknown. A recent report suggested that choroidal circulation impairment correlates with its pathogenesis. We report a rare case with simultaneous onset of AMN and central retinal vein occlusion (CRVO), which is a retinal circulation disorder.
Methods: Case report.
Results: A 44-year-old woman complained of central visual loss of the left eye for the previous 2 weeks. The patient’s visual acuity was 0.5 in the left eye (OS). Fundoscopic examination revealed a wedge-shaped, dark reddish-brown lesion at the macula, and CRVO-like retinal hemorrhages OS. Fluorescein angiography revealed retinal vasculitis and hypofluorescence corresponding to the macular lesion. The patient’s scanning laser ophthalmoscopy infrared imaging result led to a diagnosis of AMN. Two weeks after corticosteroid pulse therapy, her visual acuity improved to 1.2 OS, with improvement of macular findings and Humphrey perimetry. When the dose of oral corticosteroid was decreased, the AMN lesion worsened, with recurrence of retinal hemorrhages. Visual functions improved again after an increased dose of corticosteroid.
Conclusion: These results suggest that circulatory disorders almost simultaneously
occurred in choroidal and retinal vessels, resulting in the onset of both AMN and CRVO.

Keywords: choroidal circulation, optical coherence tomography, retinal circulation, systemic corticosteroid therapy

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