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A new needle on the block: EchoTip ProCore endobronchial ultrasound needle

Authors Dincer H, Andrade R, Zamora F, Podgaetz E

Received 22 December 2015

Accepted for publication 5 February 2016

Published 29 March 2016 Volume 2016:9 Pages 467—473

DOI https://doi.org/10.2147/MDER.S62724

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Lucy Goodman

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


H Erhan Dincer,1 Rafael Andrade,2 Felix Zamora,1 Eitan Podgaetz2

1Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, 2Section of Thoracic and Foregut Surgery, University of Minnesota, Minneapolis, MN, USA

Abstract: Endobronchial ultrasound has become the first choice standard of care procedure to diagnose benign or malignant lesions involving mediastinum and lung parenchyma adjacent to the airways owing to its characteristics of being real-time and minimally invasive. Although the incidence of lung cancer has been decreasing, it is and will be the leading cause of cancer-related mortality in the next few decades. When compared to other cancers, lung cancer kills more females than breast and colon cancers combined and more males than colon and prostate cancers combined. The type of lung cancer has changed in recent decades and adenocarcinoma has become the most frequent cell type. Prognosis of lung cancer depends upon the cell type and the staging at the time of diagnosis. The cell type and molecular characteristics of adenocarcinoma may allow individualized targeted treatment. Other malignant conditions in the mediastinum and lung (eg, metastatic lung cancers and lymphoma) can be biopsied using endobronchial ultrasound needles. Endobronchial ultrasound needle biopsies provides mostly cytology specimens due to its small sizes of needles (22 gauge or larger) which may not give enough tissue to make a definitive diagnosis in malignant (eg, lymphoma) or benign conditions (eg, sarcoidosis). EchoTip ProCore endobronchial needle released in early 2014 provides histologic biopsy material. Larger tissue biopsies may potentially provide a higher diagnostic yield and it eliminates mediastinoscopy or other surgical interventions. Here we aim to review bronchoscopic approach in the diagnosis of mediastinal lesions with emphasis of EchoTip ProCore needles.

Keywords: endobronchial ultrasound, lymph node biopsy, EchoTip ProCore, lung cancer, transbronchial needle aspiration

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