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A necrotic lung ball caused by co-infection with Candida and Streptococcus pneumoniae
Authors Yokoyama T, Sasaki J, Matsumoto K, Koga C, Ito Y, Kaku Y, Tjiri M, Natori H, Hirokawa M
Published 15 December 2011 Volume 2011:4 Pages 221—224
DOI https://doi.org/10.2147/IDR.S24269
Review by Single anonymous peer review
Peer reviewer comments 4
Toshinobu Yokoyama, Jun Sasaki, Keita Matsumoto, Chie Koga, Yusuke Ito, Yoichiro Kaku, Morihiro Tajiri, Hiroki Natori, Masashi Hirokawa
Division of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan
Introduction: A necrotic lung ball is a rare radiological feature that is sometimes seen in cases of pulmonary aspergillosis. This paper reports a rare occurrence of a necrotic lung ball in a young male caused by Candida and Streptococcus pneumoniae.
Case report: A 28-year-old male with pulmonary candidiasis was found to have a lung ball on computed tomography (CT) of the chest. The patient was treated with ß-lactams and itraconazole and then fluconazole, which improved his condition (as found on a following chest CT scan) and serum ß-D-glucan level. The necrotic lung ball was suspected to have been caused by co-infection with Candida and S. pneumoniae.
Conclusion: A necrotic lung ball can result from infection by Candida and/or S. pneumoniae, indicating that physicians should be aware that patients may still have a fungal infection of the lungs that could result in a lung ball, even when they do not have either Aspergillus antibodies or antigens.
Keywords: lung ball, necrotic lung ball, Candida, Streptococcus pneumoniae
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