A multicenter investigation of OPTI-FREE(RM) RepleniSH(RM) multi-purpose disinfecting solution impact on soft contact lens patient comfort

Glenn S Corbin¹, Linda Bennett², Louis Espejo³, Suzanne Carducci⁴, Andrew Sacco⁵, Robert Hannigan⁶, Stuart Schatz⁷

¹Wyomissing Optometric Center, Wyomissing, PA, USA; ²Bellmont, MA, USA; ³Rockville, MD, USA; ⁴Gaithersburg, MD, USA; ⁵Vestal, NY, USA; ⁶Taunton, MA, USA; ⁷College Park, MD, USA

Objective: Demonstrate that successful soft contact lens wearers using competitive multipurpose solutions report improvement in comfort with OPTI-FREE^® RepleniSH^® Multi-Purpose Disinfecting Solution (MPDS).

Methods: This 30-day, multicentered, open-label study enrolled 109 eligible soft contact lens wearers using COMPLETE^® Multi-Purpose Solution (MPS) Easy Rub^® or ReNu MultiPlus^® MPS. The test solution (OPTI-FREE^® RepleniSH^® MPDS) was dispensed for use in place of habitual care solutions. Subjects assessed their experience with their habitual solution (baseline) and the test solution (Day 30) using Likert-style questions. Contact lens acuity and biomicroscopy findings were recorded at each visit.

Results: The test solution was associated with a statistically significant improvement in instillation comfort (P = 0.02), end of day comfort (P < 0.0001), clear vision (P < 0.0001) and overall satisfaction (P < 0.001). Subjects reported the test solution enhanced their overall lens-wearing experience more effectively than their previous solution (P < 0.0001) and that they would continue test solution use after the study (P < 0.0001).

Conclusions: The test solution was effective at improving comfort and overall contact lens experience compared to COMPLETE^® MPS Easy Rub^® or ReNu MultiPlus^® MPS in successful contact lens wearers. These results indicate that changing contact lens care solutions, even in successful lens wearers, may improve comfort and overall lens-wearing experience.

Keywords: multipurpose solution, soft contact lens, disinfecting solution, patient comfort