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A fatal case of congenital pulmonary airway malformation with aspergillosis in an adult

Authors Enuh H, Arsura E, Cohen Z, Diaz K, Nfonoyim J, Cosentino P, Saverimuttu J

Received 7 November 2013

Accepted for publication 27 December 2013

Published 20 March 2014 Volume 2014:7 Pages 53—56

DOI https://doi.org/10.2147/IMCRJ.S54850

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 4


Hilary A Enuh,1 Edward L Arsura,2 Zaza Cohen,3 Keith T Diaz,2 Jay M Nfonoyim,2 Phillip J Cosentino,2 Jessie K Saverimuttu4

1Department of Internal Medicine, Richmond University Medical Center, Staten Island, NY, USA; 2Pulmonary and Critical Care Medicine, Richmond University Medical Center, Staten Island, NY, USA; 3Pulmonary and Critical Care Medicine, Rutgers, The State University of New Jersey, New Jersey Medical School, Newark, NJ, USA; 4Infectious Disease Control Unit, Richmond University Medical Center, Staten Island, NY, USA

Abstract: Congenital cystic adenomatoid malformation, currently referred as congenital pulmonary airway malformation (CPAM), is one of the rare lung malformations seen in adults. We report a case of a 59-year-old male with a chronic cough and hemoptysis that was not amenable to bronchial embolization. Further work up revealed cystic changes with fungal ball and type 1 CPAM. Patients with this condition who survive to adulthood usually suffer from recurrent respiratory bacterial infections. Only three cases of fungal involvement have ever been described. We present a fatal case, as well as the oldest patient.

Keywords: CPAM, aspergillosis, embolization

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