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A critical review of anti-adrenergic therapy in patients with heart failure and diabetes mellitus

Authors WH Wilson Tang

Published 15 November 2007 Volume 2007:3(5) Pages 639—645


WH Wilson Tang

Section of Heart Failure and Cardiac Transplantation Medicine, Department of Cardiovascular Medicine, the Cleveland Clinic, Cleveland, OH, USA

Abstract: Anti-adrenergic therapy has been widely accepted as an important therapeutic intervention in patients with chronic heart failure. However, there has been continuing controversy regarding the risks and clinical significance of metabolic effects of different anti-adrenergic drugs. This review summarizes what has been learned from clinical trial evidence regarding the benefits of anti-adrenergic drugs in diabetic patients with chronic heart failure.
Keywords: diabetes mellitus, congestive heart failure, anti-adrenergic drugs, carvedilol

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