Back to Journals » Patient Preference and Adherence » Volume 13

A Chinese and Western medication adherence scale in patients with Chronic Kidney Disease

Authors Tan J, Luo L, Zhang M, Chen H, Zhang D, Dong C, Xia B, Fu L, Tang F, Liu X, Tan Q, Wu Y

Received 5 March 2019

Accepted for publication 1 August 2019

Published 30 August 2019 Volume 2019:13 Pages 1487—1495


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Naifeng Liu

Jiaowang Tan,1,2 Li Luo,3 Min Zhang,3 Huifen Chen,3 Dingjun Zhang,3 Chendi Dong,3 Bingqing Xia,3 Lizhe Fu,1 Fang Tang,1 Xusheng Liu,1 Qinxiang Tan,2 Yifan Wu1

1Renal Division, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, People’s Republic of China; 2Renal Division, Beijing University of Chinese Medicine Shenzhen Hospital, Shenzhen, Guangdong, People’s Republic of China; 3The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China

Correspondence: Yifan Wu
Renal Division, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), No.111, Dade Road, Yuexiu District
, Guangzhou 510120, People’s Republic of China
Tel +86 13 56 032 4448

Objective: The self-reported scale is a widely used method to assess patients’ medication adherence in clinical practice, but there is still a lack of medicine adherence measurement scale for patients with Chronic Kidney Disease (CKD). Therefore, this study aimed to develop a medication adherence measurement scale of traditional Chinese medicine and Western medicine, providing a tool for evaluating medicine adherence of CKD patients.
Methods: In the preliminary stage, we formed the prediction scale after three rounds Delphi method and it was filled by 20 patients, who were selected randomly. After pre-investigation and language adaption, we adjusted the prediction measurement scale which included 31 items based on Knowledge-Attitude-Belief Theory. Then, 222 CKD patients in Guangdong Hospital of traditional Chinese Medicine were investigated by this 31-item scale. We screened 31 items by Items analysis theory, including critical ratio, item correlation analysis, internal consistency analysis, principal component analysis and other methods. The left 26 items made up a formal scale. We collected and analyzed data of the 26-item scale and Chinese version of MGL scale, and took their scores correlation analysis as the criterion validity of the 26-item scale. At the same time, we evaluated content validity, Cronbach alpha coefficient and retest reliability of the 26-item scale.
Results: We developed a scale with 26 items and 5 dimensions finally. In the validation analysis, the scale had good construct validity and content validity. The Pearson relation index between respective scores of the scale and Chinese version of MGL scale was 0.426, P<0.01. The scale also had good reliability as its 0.915 in Cronbach alpha, 0.753 in retest reliability and P<0.01.
Conclusion: The scale revealed great reliability and validity, which could be used as a measurement tool to evaluate the medication adherence of patients with CKD.

Keywords: chronic kidney disease, traditional Chinese medicine, adherence medication, scale, Delphi method

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]