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A case of Alagille syndrome complicated by intraocular lens subluxation and rhegmatogenous retinal detachment

Authors Fukumoto M, Ikeda T, Sugiyama T, Ueki M, Satou T, Isizaki E

Received 6 February 2013

Accepted for publication 30 April 2013

Published 17 July 2013 Volume 2013:7 Pages 1463—1465


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Masanori Fukumoto, Tsunehiko Ikeda, Tetsuya Sugiyama, Mari Ueki, Takaki Sato, Eisuke Ishizaki

Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan

Abstract: This case report describes a case of Alagille syndrome with developing intraocular lens subluxation and rhegmatogenous retinal detachment 4 years after cataract surgery. A 15-year-old female patient with Alagille syndrome-associated cataracts in both eyes underwent phacoemulsification aspiration and intraocular lens implantation. Four years postoperative, intraocular lens subluxation developed in her left eye. For treatment, extraction of the dislocated intraocular lens, anterior vitrectomy, and intraocular lens fixation was performed. Three weeks later, the patient developed rhegmatogenous retinal detachment, which was well-treated by pars plana vitrectomy. Cataract surgery needs to be performed carefully in patients with Alagille syndrome due to the weakness of the zonule of Zinn. Careful postoperative observation is necessary for patients with Alagille syndrome who have undergone intraocular surgery in order to facilitate early detection of a possible rhegmatogenous retinal detachment.

Keywords: Alagille syndrome, cataract, retina, surgery

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