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38-year-old woman with recurrent abdominal pain, but no fever
Authors Iwata K , Toma, Yachie A
Received 14 February 2012
Accepted for publication 22 February 2012
Published 22 March 2012 Volume 2012:5 Pages 265—268
DOI https://doi.org/10.2147/IJGM.S30867
Review by Single anonymous peer review
Peer reviewer comments 2
Kentaro Iwata1, Tomoko Toma2, Akihiro Yachie2
1Department of Infectious Diseases, Kobe University Hospital, Kobe, Japan; 2Department of Pediatrics, Graduate School of Medical Science and School of Medicine, Kanazawa University, Kanazawa, Japan
Abstract: A 38-year-old woman presented with 2 days history of left-flank pain. She had similar episodes of abdominal pain as well as chest pain several times, but symptoms disappeared spontaneously. Each time she developed pain, there was no fever. After ruling out common causes of recurrent abdominal pain, familial Mediterranean fever (FMF) was considered as a potential diagnosis. Genetic tests revealed multiple heterozygote mutations, which may be associated with FMF. Patients with Mediterranean fever mutations may present with atypical presentations without fever, like in this case. Astute clinical suspicion is required to make an accurate diagnosis.
Keywords: familial Mediterranean fever, MEFV mutation, afebrile
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